Ates of Experimental Brain Ischemia: Quantified Eeg Analy

Cerebral ischemia of thrombotic or embolic origin is still a major cause of morbidity and m o r t a l i t y, mainly because the cellular mechanisms that lead to primary and secondary brain damage are still incompletely understood. This has stimulated many authors to develop experimental models to study the modification of biological and neurophysiological parameters in cerebral ischemia. The most common techniques are: – microsurgical occlusion of the middle cerebral artery (MCA) by transorbital approach (1,2); – intravascular embolization by microspheres or by homologous blood emboli (3-6); – photothrombosis induced by Rose Be n g a l dye (7). THE INTRAVASCULAR EMBOLIZAT I O N METHOD